Academy award-winning filmmaker James Cameron says he believes testosterone is a "toxin" that men should "slowly work out of your system." .His comments came during a sit down with The Hollywood Reporter earlier this week as the legendary director — known for his blockbuster hits like Titanic and the Terminator and Aliens franchises — mused about the decade-long making of Avatar: The Way of Water, his long-anticipated follow up to the first Avatar. .During the discussion, Cameron spoke about his earlier F-bomb-dropping clashes with executives over budgets with some regret.."A lot of things I did earlier, I wouldn't do — career-wise and just risks that you take as a wild, testosterone-poisoned young man," said Cameron in the interview. "I always think of [testosterone] as a toxin you have to slowly work out of your system.".Cameron's latest installment in the Avatar franchise — starring the returning Sam Worthington as Jake Sully, Zoe Saldana as Neytiri, and Sigourney Weaver as Kiri — is set for a December 16 release..His first Avatar, although production was started in 1994 with a planned release in 1999, was finally released in 2009. Its official budget was pegged at $237 million, but other estimates said costs ranged between $280 million and $310 million for production and $150 million for promotion. The box-office smash broke records and became the highest-grossing film in the world for nearly a decade until it was dethroned by Avengers: Endgame in 2019. .After adjusting for inflation, the first Avatar grossed more than $3 billion since its release and is the second-highest-grossing movie of all time after Gone with the Wind. .The official trailer for Cameron's second installment was posted November 21. .Worthington told The Tonight Show Starring Jimmy Fallon the third Avatar is "about 80, 90%" filmed to date and parts of the fourth film have already been shot.
